Nico P E Vermeulen Selected Research

amodiaquine quinoneimine

1/2018

Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells.

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Nico P E Vermeulen Research Topics

Disease

14	Drug-Related Side Effects and Adverse Reactions 03/2018 - 08/2007
3	Chemical and Drug Induced Liver Injury 03/2018 - 06/2016
3	Neoplasms (Cancer) 01/2015 - 05/2002
3	Carcinogenesis 02/2004 - 05/2002
2	Necrosis 01/2020 - 06/2011
2	Hepatocellular Carcinoma (Hepatoma) 10/2018 - 05/2002
2	Agranulocytosis (Granulocytopenia) 01/2018 - 06/2017
2	Mitochondrial Diseases (Mitochondrial Disease) 03/2012 - 03/2011
1	Liver Failure 01/2020
1	Infections 11/2018
1	Starvation 10/2018
1	Malaria 01/2018
1	Acute Liver Failure (Fulminant Hepatic Failure) 01/2017
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Exanthema (Rash) 12/2016
1	Asthma (Bronchial Asthma) 07/2015
1	Hypersensitivity (Allergy) 12/2014
1	Inflammation (Inflammations) 03/2012
1	Pain (Aches) 03/2012
1	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 02/2007

Drug/Important Bio-Agent (IBA)

11	Pharmaceutical PreparationsIBA 01/2020 - 08/2007
8	Diclofenac (SR 38)FDA LinkGeneric 03/2018 - 03/2011
6	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020 - 04/2014
4	Proteins (Proteins, Gene)FDA Link 10/2018 - 08/2007
4	Clozapine (Clozaril)FDA LinkGeneric 01/2018 - 09/2010
3	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 11/2018 - 03/2012
3	EnzymesIBA 11/2018 - 03/2004
2	Estrogens (Estrogen)FDA Link 01/2017 - 02/2004
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 07/2016 - 03/2012
2	ProdrugsIBA 01/2015 - 03/2004
2	Mefenamic Acid (Pontal)FDA Link 12/2014 - 04/2014
2	O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfateIBA 01/2014 - 09/2010
2	Antipsychotic Agents (Antipsychotics)IBA 10/2013 - 12/2011
2	Protein Isoforms (Isoforms)IBA 05/2002 - 05/2002
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Amino Acids FDA Link 10/2018
1	Membrane Transport Proteins (Biological Pump)IBA 10/2018
1	UbiquitinIBA 03/2018
1	Tyrosine (L-Tyrosine)FDA Link 03/2018
1	Deubiquitinating EnzymesIBA 03/2018
1	desethylamodiaquineIBA 01/2018
1	amodiaquine quinoneimineIBA 01/2018
1	NRH - quinone oxidoreductase2IBA 01/2018
1	Amodiaquine (Camoquin)FDA Link 01/2018
1	Therapeutic UsesIBA 06/2017
1	Aromatase (CYP19)IBA 01/2017
1	Aromatase InhibitorsIBA 01/2017
1	quinone methideIBA 12/2016
1	Reverse Transcriptase InhibitorsIBA 12/2016
1	Epoxy Compounds (Epoxides)IBA 12/2016
1	Nevirapine (Viramune)FDA Link 12/2016
1	NucleosidesIBA 12/2016
1	Tolcapone (Tasmar)FDA Link 06/2016
1	SuspensionsIBA 06/2016
1	IsocyanatesIBA 07/2015
1	GlucuronidesIBA 11/2013
1	CytochromesIBA 12/2012
1	Analgesics (Analgesic Drugs)IBA 09/2011
1	Thymidine Monophosphate (TMP)IBA 11/2008
1	AcidsIBA 02/2007
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 02/2007
1	OxygenasesIBA 02/2007
1	Cisplatin (Platino)FDA LinkGeneric 03/2004
1	Irinotecan (Camptosar)FDA LinkGeneric 03/2004
1	Tirapazamine (SR 4233)IBA 03/2004
1	trofosfamideIBA 03/2004
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 03/2004
1	Dacarbazine (DIC)FDA LinkGeneric 03/2004
1	Daunorubicin (Cerubidine)FDA LinkGeneric 03/2004
1	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2004
1	Amifostine (Ethyol)FDA LinkGeneric 03/2004
1	Etoposide (VP 16)FDA LinkGeneric 03/2004
1	Fluorouracil (Carac)FDA LinkGeneric 03/2004
1	Ifosfamide FDA LinkGeneric 03/2004
1	Melphalan (Alkeran)FDA LinkGeneric 03/2004
1	Thioguanine (Tioguanine)FDA Link 03/2004
1	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 03/2004
1	Epirubicin (Ellence)FDA LinkGeneric 03/2004
1	Ganciclovir (Cytovene)FDA LinkGeneric 03/2004
1	Mitomycin (Mitomycin-C)FDA LinkGeneric 03/2004
1	Paclitaxel (Taxol)FDA LinkGeneric 03/2004
1	AnthracyclinesIBA 03/2004
1	Vitamin K 3 (Menadione)FDA Link 03/2004
1	SelenocysteineIBA 05/2002
1	Messenger RNA (mRNA)IBA 05/2002
1	LyasesIBA 05/2002
1	glutathione S-transferase alphaIBA 05/2002
1	XenobioticsIBA 05/2002

Therapy/Procedure

1	Therapeutics 01/2015